Chemistry & Biology 2002 9, 779-780.
Stochastic Sensing of IP3 Has Far-Reaching Consequences
E. V. Anslyn and J. B. Shear
Hagan Bayley's group at Texas A&M University has devised a stochastic sensing methodology for the quantitation of the second messenger inositol 1,4,5-trisphosphate. The unique sensing scheme is very selective and has the potential to measure cytosolic concentrations of IP(3).