Sociomicrobiology in engineered landscapes

Jodi L Connell, Marvin Whiteley & Jason B Shear

Nature Chemical Biology 8, 10–13 (2012)

A growing body of evidence points to the importance of microcolonies in the dissemination of bacteria, yet there is a dearth of tools for systematically assessing the behavior of cells within such communities. New strategies for landscaping three-dimensional culture environments on microscopic scales may have a critical role in revealing how bacteria orchestrate antibiotic resistance and other social behaviors within small, dense aggregates.